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Matthew Perry, Best Known for Role in ‘Friends,’ Dies from Acute Effects of Ketamine, Autopsy Report Reveals

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Key takeaways:

  • Matthew Perry died from the acute effects of ketamine, according to an autopsy report released by the Los Angeles Medical Examiner Office.
  • The autopsy report lists contributing factors in Perry’s death as drowning, coronary artery disease and the effects of buprenorphine.
  • The report states that Perry had been receiving ketamine therapy for depression and anxiety and that his death was accidental with no signs of foul play.

Actor Matthew Perry, best known for his role in the hit sitcom “Friends,” has died from the acute effects of ketamine, according to an autopsy report released Friday by the Los Angeles Medical Examiner Office.

The report states that Perry, 54, was found unresponsive in late October, “floating face down in the heated end of pool.” The autopsy report also lists contributing factors in Perry’s death as drowning, coronary artery disease and the effects of buprenorphine, which is used to treat opioid use disorder.

On the day of Perry’s death, first responders went to a home in Pacific Palisades based on a 911 call at 4:07 p.m. about a “water emergency” of an unknown type, according to the Los Angeles Fire Department.

The autopsy report also revealed that Perry had been receiving ketamine therapy for depression and anxiety. Perry had also reportedly struggled with addiction for many years, although he had been clean for 19 months prior to his death.

The report states that Perry’s death was accidental and that no signs of foul play were suspected. Perry’s fans and friends have been mourning his death since it was announced in late October.

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