NASA’s Artemis II mission is set to launch Wednesday evening, marking the agency’s first crewed lunar flight in over 50 years with astronauts Reid Wiseman, Victor Glover, Christina Koch, and Canadian Jeremy Hansen embarking on a 10-day journey around the moon. Preparations have gone smoothly, including fueling the Space Launch System rocket and Orion capsule, with an 80% chance of favorable weather for liftoff from Kennedy Space Center. This historic mission, the first to carry humans on NASA’s new lunar spacecraft, is a crucial step toward a planned lunar landing in 2025 and features a diverse, experienced crew ready to reignite human exploration of the moon.